Leukemia is not a disease that requires bone marrow transplantation. Leukemia is a generic term for a large group of diseases, which are divided into several subtypes. There are subtypes of leukemia that can be cured by oral medications and chemotherapy regimens: first, acute promyelocytic leukemia, which can be cured clinically by simple combination chemotherapy in low-risk patients. Secondly, in chronic granulocytic leukemia, due to the introduction of targeted tyrosine kinase inhibitors, it is also possible to achieve clinical cure with oral drugs alone. Finally, patients with chronic lymphocytic leukemia can now also be treated with oral BTK inhibitors such as ibrutinib, which can achieve an efficiency of 70%-80%. Of course there are other types of leukemia that require consideration of bone marrow transplantation if the risk level is high and the patient is young.