If the breast cancer is ulcerated without surgery, it is difficult to reach the degree of self-healing, and the best way is to find radical surgery to achieve self-healing, patients need to follow the doctor’s instructions for drug treatment, surgical treatment and so on. 1. Drug treatment: Usually, patients can use chemotherapeutic drugs such as epirubicin, doxorubicin, docetaxel, paclitaxel and so on according to doctor’s prescription, which mainly inhibit biochemical metabolic process of cancer cells. For pre and postmenopausal women, anti-estrogen drugs such as tamoxifen and toremifene can be used in combination, and postmenopausal women can also be treated with aromatase inhibitors such as letrozole and exemestane. At the same time, patients can also use trastuzumab, lapatinib, pyrrolitinib, patuximab and other targeted drugs. 2. Surgery: Usually, for patients with early stage breast cancer and the need of breast preservation, and the maximum diameter of tumor is less than or equal to 3cm, breast preservation surgery can be carried out according to the doctor’s instruction, while patients with carcinoma in situ, microscopic carcinoma and those who are not suitable to undergo radical surgery can choose to undergo total mastectomy. As for patients with relatively better conditions, they can choose to undergo radical surgery, extended radical surgery, modified radical surgery and so on. It is recommended that patients with breast cancer ulcers should undergo systematic treatment under doctor’s guidance in time, which is usually difficult to heal by itself.