A patch of bumps and itching on the hands may be associated with conditions such as contact dermatitis, eczema, or ringworm. Treatment requires anti-allergy, anti-itching, and anti-fungal medications, respectively. 1. Contact dermatitis: it is an inflammatory reaction that occurs when the skin comes into contact with some kind of allergy or irritant. The first step in the treatment is to remove the causative factors, such as washing the affected skin. Secondly, anti-allergy medication can be given, such as topical compound dexamethasone cream, dieldrin cream and so on. 2. Eczema: it is an allergic disease and an inflammatory disease, the first step of the treatment is to actively remove the causative factors, and then give the symptomatic anti-allergic drug treatment, such as oral loratadine tablets, topical hydrocortisone butyrate cream and so on. 3. Ringworm: It is caused by ringworm infection, and the primary measure of treatment is to give anti-fungal medication, such as clotrimazole cream and ketoconazole ointment. In the course of treatment, it is necessary to keep the skin of the hands clean to avoid cross-infection. In order to ensure the safety and effectiveness of the medication, it must be used under the guidance of a doctor.