Whether mycoplasma infection in children is serious or not is related to the site of infection and the degree of infection. If mycoplasma infection affects the upper respiratory tract, it is usually not serious, and if it develops into the lower respiratory tract and causes other organ involvement, it is relatively serious. If mycoplasma infection causes upper respiratory tract infection, resulting in the emergence of acute pharyngitis, acute tonsillitis, usually not particularly serious, after active treatment, the prognosis is good. If mycoplasma infection causes lower respiratory tract infection, leading to acute bronchitis, acute mycoplasma pneumonia, leading to heart, kidney and other organs involved, there may be obvious cough, fever, shortness of breath and other symptoms, this is relatively serious. If the mycoplasma infection has caused the infection of the respiratory system of the lungs, it can lead to some immune aspects of the response, this immune response sometimes invades the tissues outside the lungs, such as the brain or the heart, such as mycoplasma infection caused by myocardial constriction, mycoplasma encephalitis, and so on, and this is a very serious situation. Mycoplasma infections in children, whether serious or not, need to consult a doctor in a timely manner and follow the doctor’s instructions for standardized treatment.