Mycoplasma infection is a sexually transmitted disease. Mycoplasma can be present in healthy carriers, while detection rates are higher in sexually promiscuous individuals, homosexuals, prostitutes, and gonorrhea patients. The higher the number of sexual partners and the greater the index of sexual activity, the higher the rate of infection. Mycoplasma is another type of microscopic pathogens different from bacteria and fungi. There are more than 80 species of mycoplasma genus, and mycoplasmas related to humans are Mycoplasma pneumoniae (MP), Mycoplasma humanum (MH), Mycoplasma urealyticum (UU) and Mycoplasma genitalium (MG), the former causing pneumonia and the latter three causing genitourinary tract infections. I. Effects on the female reproductive system Mycoplasma urealyticum can invade the urethra, cervix and vestibular gland, causing urethritis, cervicitis and vestibular glanditis; when infected upstream, it can cause endometritis, pelvic inflammatory disease and tubal inflammatory disease, especially tubal inflammatory disease. Pathological changes in female reproductive organs caused by Mycoplasma hyopneumoniae infection are an important cause of infertility. Domestic and foreign data suggest that the culture positivity rate of Mycoplasma urealyticum in cervical mucus and semen of infertile couples is as high as 50% or more, which shows that there is a correlation between Mycoplasma urealyticum infection and the occurrence of infertility. Another cause of poor performance due to Mycoplasma urealyticum infection is miscarriage, and some people have detected positive rates of Mycoplasma urealyticum in tissues from miscarriages of up to 40% or more. Therefore, the possibility of having Mycoplasma urealyticum infection should be considered for unexplained miscarriages, especially in those with multiple miscarriages. Inflammatory adhesions in incompletely obstructed fallopian tubes caused by Mycoplasma hyopneumoniae infection can narrow the lumen and make it inaccessible, and are also an important cause of ectopic pregnancy. After pregnancy, women are more susceptible to infection by Mycoplasma decidua due to the increase in progesterone, which suppresses cellular immunity and decreases the body’s resistance, and perinatal infections caused by Mycoplasma decidua have become a new problem in modern obstetrics. Mycoplasma urealyticum can be transmitted vertically through the placenta or spread upstream from the lower genital tract of pregnant women, causing intrauterine infection, both of which can lead to miscarriage, premature birth, intrauterine growth retardation, low birth weight, premature rupture of fetal membranes, and even fetal death in the uterus and a series of other adverse consequences. Second, there are effects on the fetus Mycoplasma infection itself can cause infertility, miscarriage, premature birth, low birth weight babies and fetal malformations. But first of all, it depends on how many months of pregnancy you are infected, if it is early pregnancy, the fetus may be affected, the fetus in the middle and late pregnancy when the organs have developed better impact is not significant. The two can lead to miscarriage, premature birth, intrauterine growth retardation, low birth weight, premature rupture of membranes, and even fetal death in the womb. During labor and delivery, the fetus is also susceptible to infection when it is delivered through the birth canal. The most common infections are neonatal ophthalmia, followed by neonatal respiratory infections, otitis media, and laryngitis. For mycoplasma chlamydia is a serious problem that affects the fetus and self-birth, and can cause disease in the family and the newborn. Diagnostic tests Blood count Peripheral blood white blood cell count is generally normal, eosinophilia. 1. X-ray examination The chest X-ray of Chlamydia pneumonia is non-specific, mostly unilateral infiltration of the lower lobe, showing segmental pneumonia, and in severe cases, extensive bilateral pneumonia. The chest X-ray of Chlamydia trachomatis pneumonia shows bilateral extensive interstitial and alveolar infiltrates, hyperinflation signs are more common, and occasionally large lobe solid changes are seen. 2, direct smear microscopy Take pharyngeal secretions, sputum, respiratory teach membrane or other parts of the specimen to do smear, GZmesa staining, the original body stained red, the beginning of the body stained dark blue. Chlamydia trachomatis inclusion body because it contains glycogen. 801 staining stained brown. 3, rapid antigen detection More than the use of monoclonal antibodies direct immunofluorescence detection of chlamydia in the specimen, but also the application of 2I-Isa method to join the anti-chlamydial antibody, enzyme-labeled antibody 18G and substrate for colorimetric quantitative detection. These two methods are simple and sensitive. 4, chlamydia isolation Chlamydia pneumoniae culture is best used Hela cells or Hep a 2 cells, generally take tracheal or nasopharyngeal aspirate as clinical specimens, timely inoculation. Chlamydia identification using Hela cells or Hep a 2 cells after culture by specific monoclonal fluorescent antibody method (MFA), the technique is highly sensitive, specific, such as early collection of specimens, positive results can be obtained within 48h. 5, serological examination using complement binding test, the recovery period serum antibody potency than the acute period serum potency increased by 4 times or more, that is, there is diagnostic significance, but no early diagnostic significance. Trace immunofluorescence method (MrF) is applicable to Chlamydia trachomatis. 6, PCR technology Ordinary PcR technology to detect Chlamydia pneumoniae specific DNA, has the advantages of rapid, simple, specific, and higher sensitivity than cell separation technology, but the effect in the detection of pharyngeal swab in the specimen is not good enough. Detection by set PcR (nPcR) can significantly improve its sensitivity. 7, symptoms (1) male infection with mycoplasma symptoms prone to prostatitis, epididymitis, etc.; the results of infection, resulting in serious infection of the secretions in these areas; directly affect the vitality and dynamics of sperm, resulting in significantly lower sperm quality and a significant increase in the number of dead sperm; the number of sperm with the ability to conceive is reduced, reduced motility, abnormal morphology, some have low capacity or loss, loss of access to the egg and its This can lead to infertility or threaten the quality of human reproduction and the ability to reproduce. (2) Symptoms of mycoplasma infection in women In the early stages of infection in women, the vagina and cervix are usually invaded. Inflammatory reactions occur in these organs, resulting in increased secretions. The leukorrhea has an abnormal odor and some feel a slight discomfort in the genital tract. It is the concealment of the symptoms that often makes the patient unaware of the invasion of human mycoplasma. If not treated in time the infection will continue. This causes inflammation of the endometrium and swelling of the cilia of the fallopian tubes, resulting in impairment of the physiological functions of these organs, directly affecting the entry of sperm into the uterus and fallopian tubes affecting sperm-egg union and the normal functioning of the fertilized egg. Even if pregnancy occurs, it can easily lead to aborted embryos, fetal death, spontaneous abortion, and low birth weight babies. Mycoplasma humanum infection in women can also cause pyelonephritis, pelvic inflammatory disease post-abortion fever, postpartum fever, non-gonococcal urethritis and other diseases. Fourth, treatment 1, Western medicine therapy Strongylin 100mg orally, twice a day for 7-14 days or azithromycin 1g, single dose orally, half-life up to 60 hours, once orally, can maintain the effective concentration for 5 days; fluazinic acid 0.2, orally, twice a day for 7-14 days. Pathogenic treatment mainly uses five some lotions, usage: 6h1 time. 2.Chinese medicine treatment Restore the balance of vaginal flora to prevent recurrence Through Chinese medicine conditioning, it can balance and eliminate the living environment of pathogenic body to prevent recurrence. Commonly used herbal ingredients components are Chai Hu, Angelica sinensis, Atractylodes jin Yin Hua, forsythia, psyllium, peach kernel, safflower, etc. It can kill all kinds of bacteria, viruses, pathogens, mycoplasma, chlamydia, gonorrhea turn negative, unblock the fallopian tube, achieve pain relief, regulate menstruation and other therapeutic effects! Five, prevention 1, active exercise weekdays should be planned to exercise, sleep in the room to keep the air fresh, the temperature is appropriate. Windows should be opened for sleep since early childhood and should be at least indirectly ventilated. Make full use of sunbathing, airbathing and waterbathing. Strengthening physical fitness is the first important factor to prevent diseases. 2, hygiene, avoid cross-infection Do not go to crowded, poorly ventilated theaters, department stores, supermarkets and other places. Avoid contact with patients as much as possible, and seek medical treatment nearby if you are sick, and run less to big hospitals to shorten the waiting time. In the past, it was thought that respiratory diseases were transmitted only by breathing, but in recent years it has been confirmed that contact transmission is an important mode of transmission. Special attention should be drawn to the fact that children should not be allowed to smoke passively, being smoked is an important reason to increase the number of children suffering from respiratory diseases. 3, drug prevention Certain Chinese and Western drugs can improve the body’s cellular and humoral immune function, it is best to use drugs under the guidance of a doctor. 4.Vaccination Some places use attenuated virus vaccine, but it is not yet universally applied, and vaccines have been designed for prevention, but the protection rate is only 50%, and there is no systematic report on antibiotic prevention. 6. Daily precautions 1. Avoid sexual intercourse before cure. 2, no alcohol, no spicy food, drink more water. 3, do the necessary isolation in the family, bath towels, washbasins, bathtubs, toilets and other separate use, or disinfection after use. 4.Spouse or sexual partner should go to hospital for examination and treatment. 5. Pay attention to safe sex in the future, and use condoms correctly when at high risk. 6.Use pH4 weak acidic feminine care solution for daily cleaning of the pubic area.