Anesthesia for the thyroid puncture procedure is local infiltration anesthesia under the skin and around the location of the nodule. Thyroid puncture is less invasive and less painful, and local infiltration anesthesia is usually used. Anesthesia for thyroid puncture is usually given at the puncture site, which is where the lesion is located. If the lesion is obviously palpable, local anesthesia and puncture can be performed after palpation; if the lesion is smaller or deeper and difficult to palpate, it is necessary to perform the procedure under ultrasound guidance, and local anesthesia and puncture can be performed at the corresponding location after locating the lesion. For anesthesia, 2-3 ml of 2% lidocaine is usually used, and the syringe is advanced obliquely to anesthetize around the puncture point in multiple points and directions. After anesthesia, the syringe is withdrawn and pressure is applied for a while to wait for the anesthesia to take effect and then the puncture can begin. Patients are advised to undergo this test after fully understanding the benefits and risks of the puncture procedure, and to proceed aggressively with treatment based on pathologic findings after the test.