Persimmon stones are formed in the acidic environment of the stomach after eating large amounts of persimmons. The pathogenesis is mainly due to the presence of red tannin and yabutrol, gum, and pectic acid in persimmons. When a large amount of persimmon is eaten on an empty stomach, the red tannin combines with protein to form tannin protein, which is a large molecule but not easily soluble in water, and precipitates in the stomach. Larger persimmon stones are located in the stomach, causing stomach discomfort, gastric ulcers, gastric bleeding and other symptoms; some small persimmon stones can enter the small intestine, causing symptoms of intestinal obstruction. Treatment: Smaller persimmon stones can be removed under gastroscopy, while larger stones require surgery. In case of intestinal obstruction, if there is no acute perforation symptom, conservative treatment can be applied, such as growth inhibition, anti-infection and other symptomatic treatment.