Patients with leukemia often show signs of sternal pressure pain, especially common in the middle and lower parts of the sternum, which is the most hematopoietic bone in the body and is a flat bone with a strong hematopoietic function. When leukemia occurs, due to the disorderly proliferation of leukemia cells in the bone marrow, the number of leukocytes increases significantly, resulting in an increase in the number of leukocytes in the sternum, causing an increase in sternal pressure, which will increase even more significantly when pressing on the sternum, and will cause the pulling of the endosteal and eposteal membranes of the sternum, causing pressure pain in the sternum. When the number of leukemia is reduced and in complete remission after chemotherapy for leukemia patients, the number of leukemia cells in the sternum decreases, the pressure decreases, and the signs of sternal pressure pain disappear. Leukemia patients are prone to sternal pressure pain, and the common site is in the middle and lower sternum.