Hepatitis B half 25 positivity needs to be determined by liver function and hepatitis B DNA to determine if treatment is needed. Hepatitis B two half 25 positive refers to hepatitis B surface antibody and hepatitis B core antibody positive, these two positive may indicate that the previous infection of hepatitis B, now in a state of recovery, but at this time it is recommended to test the liver function and hepatitis B DNA, if the liver function is normal, and the viral DNA has turned negative, it means that the recovery has been achieved, no need for further treatment. In another case, the patient is in the recovery period after infection, although the body has cleared the hepatitis B virus, but there is still a small amount of hepatitis B virus left in the blood. In order to confirm the diagnosis, liver function tests and viral DNA tests are needed. If the liver function is abnormal and the viral DNA is positive, then active treatment is needed. In terms of treatment, oral nucleotide antiviral drugs such as entecavir should be taken under doctor’s supervision. Hepatitis B patients need to regularly review the liver function and hepatitis B virus DNA quantification, if there is any abnormality, please take timely treatment.