Before leukemia bone marrow transplantation should be combined with the patient’s disease staging classification, age, etc. to choose the appropriate treatment plan. It mainly includes general treatment, drug treatment, chemotherapy, radiotherapy and so on. 1. Acute leukemia patients should pay attention to rest, supplement nutrition, can use blood cell separator for single collection and removal of excessive white blood cells. Severe anemia can be treated with oxygen, transfusion of concentrated red blood cells, etc. for component transfusion. Patients with abnormal coagulation function can be infused with blood products such as fibrinogen and plasminogen complex to supplement coagulation factors and improve bleeding symptoms. 2. Elderly patients with chronic granulocytic leukemia are generally recommended to use tyrosine kinase inhibitors such as imatinib and dasatinib for molecular targeted therapy. 3. Patients with acute lymphoblastic leukemia can use chemotherapeutic drugs such as vincristine, Zoerythromycin, and cyclophosphamide to rapidly remove a large number of leukemia cells in the patient’s body, and chemotherapeutic drugs commonly used in patients with chronic lymphoblastic leukemia include nitrogen mustard phenylbutyrate and fludarabine. 4. Radiation therapy can be used for those who have unsatisfactory chemotherapy effect and patients with central nervous system leukemia. Although the cure rate of leukemia is low, some patients with acute leukemia can be cured, and it is recommended that patients actively seek medical treatment and standardize the treatment under the guidance of doctors. All of the above drugs should be used reasonably under the guidance of a doctor, and avoid self-medication.