Condyloma acuminatum, also known as acromegaly, genital warts, acromegaly, and venereal warts. They are epidermolysis bullosa-like growths on the genitals, perineum, and anus (and rarely in the armpits, breasts, mouth, ears, and throat) caused by human papilloma virus infection. It is the most common sexually transmitted disease worldwide. Recurrent attacks are one of the characteristics of the disease, especially urethral condyloma acuminata is difficult to treat. In the past, general laser treatment was generally used, but the treatment is painful for the patient, recovery after treatment is slow, and it is easy to produce urethral scarring that leads to stricture. The particulars of the urethral warts are more difficult to treat and easy to recur, and the patient is in great pain during treatment and easy to produce urethral stenosis after treatment, which has become a problem that has plagued dermatologists for many years. The latest Ala photodynamic therapy is introduced to treat urethral warts with satisfactory results. 5-aminoketovaleric acid photodynamic therapy, referred to as Ala photodynamic therapy, is a joint application of photosensitizers and the corresponding light source, through the photodynamic reaction to selectively destroy the lesion tissue of the new technology. It has the characteristics of high cure rate, low recurrence rate and good safety. Especially for male urethral warts, this method is the best and sometimes even the only treatment option. This technique features: 1. Good selectivity. 2, small trauma. As the treatment is highly selective, can avoid and significantly reduce the surgery and other laser treatment caused by trauma and pain, and no ulcers and scars formed. 3.Less pain. No obvious pain during treatment. 4.It can eliminate the hidden lesions (subclinical infection), and the recurrence rate is low. 5, repeatable treatment, lesion cells will not produce resistance to photosensitive drugs. Treatment process: 1, local routine disinfection → dressing Ira 3 hours → 635nm PDT laser treatment instrument local irradiation 20min. 2, local topical antibiotics to prevent infection.