In men, warts that grow on the outside of the penis or at the urethra are relatively easy to detect and can be removed by following the treatment for warts at the skin. Patients with warts inside the urethra, on the other hand, are usually diagnosed because of painful urination. These patients often visit a urologist, who assists the dermatologist with diagnosis and follow-up treatment through urethroscopic examination. In women, warts that grow outside the vagina, in areas like the labia, urethra, and perineum, can usually be treated by a dermatologist. However, if the growth is deeper, such as in the vaginal wall or the cervical opening, a gynecologist will need to be consulted. Also, warts that grow in the perineum area need to be distinguished from pseudoacanthomas. It is important to note that there is a possibility of false positive pathological examination. Therefore, the diagnosis of condyloma acuminatum requires a combination of symptoms, pathology, PCR amplification, and also a comprehensive diagnosis based on the corresponding medical history and partner morbidity. In other words, not one of the test results shows positive, it is definitely condyloma. For the treatment of female warts, when the warts are outside the vagina, the treatment is not different. However, when warts grow on the walls of the vagina or at the cervix, treatment with topical medications is more effective. It is safer to use a vaginal dilator to open up the vagina and apply medications such as trichloroacetic acid and tincture of demodex. In contrast, when cryotherapy and laser therapy are treated too deeply, they tend to penetrate the cervix and cause new damage to the patient. Therefore, cryotherapy, laser therapy or photodynamic therapy will only be considered when continued medication is ineffective. In addition, when one spouse has warts that are visible to the naked eye, I recommend that the other spouse is best tested with PCR amplification. This is because there is a greater chance of potential infection in the other partner. This is a very good way to get the most out of your life.