The genital warts caused by condyloma acuminatum, during pregnancy due to the secretion of chorionic gonadotropin, estrogen and progesterone, increased blood flow and secretions in the reproductive tract, active replication of human papilloma virus and low immune function of the body cells, the warts during pregnancy tend to develop into bulky, multiple and recurrent and difficult to eradicate. Although some scholars believe that the rate of intrauterine transmission is mainly related to HPV infection in maternal blood, so far, there are no reports of CA causing abortion, preterm birth, stillbirth and teratogenicity to the fetus and newborn. If the wart is growing rapidly, recurring very frequently and causing great physiological and psychological burden to the patient, termination of pregnancy can be considered, but for general and especially for precious children, cesarean delivery can avoid large warts blocking the birth canal, bleeding from warts and vertical transmission of neonatal pharyngeal, vulvar and anal papillomatosis. The chance of the newborn’s pharynx, vulva and anal papillomatosis. In the case of multiple warts, mainly in the vulva and perineum, electrocautery, microwave and cryotherapy can be given in stages, in small quantities, without chemotherapy, and without deep vaginal and cervical treatment to avoid secondary infection, abortion and early teratogenesis. The authors treated 62 CA cases with multiple small warts on the inner and outer labia minora, vaginal entrance, and anal folds with local laser and cryotherapy, so we tend to give various forms of conservative treatment for CA in pregnancy with active, comprehensive, and careful monitoring, and choose a reasonable way of delivery, not necessary to terminate the pregnancy.