Whether nephrotic syndrome can be completely cured mainly depends on the type of pathology and the effect of treatment. If the pathologic type is mild, it is possible to be completely cured after active treatment; if the pathologic type is severe and the treatment effect is not good, it may not be cured. Nephrotic syndrome is mainly characterized by massive proteinuria, hypoproteinemia, edema and hyperlipidemia. Its pathologic type can be seen in microscopic lesion nephropathy, proliferative glomerulonephritis, focal segmental glomerulosclerosis, membranous nephropathy and mesangial capillary glomerulonephritis. If the pathologic type is mild, such as microscopic lesion nephropathy and mild thylakoid proliferative glomerulonephritis, the degree of pathology is more mild. Microscopic lesion nephropathy can be treated with glucocorticoids to achieve complete clinical remission. Mild thylakoid proliferative glomerulonephritis can be relieved and clinically cured after active treatment. However, the possibility of disease recurrence due to infection, exertion and other factors cannot be ruled out. If the pathology type is focal segmental glomerulosclerosis, thylakoid glomerulonephritis, etc., the treatment effect is not good, and usually can not achieve a complete cure. Patients with nephrotic syndrome are advised to go to regular hospitals in time and receive standardized treatment under the guidance of doctors.