Separation of the toenail from the flesh can be treated with general therapy if it is caused by trauma, etc. Hormone therapy can be used if it is caused by psoriasis, and antifungal medication can be used if it is caused by a fungal infection. Separation of the toenail from the flesh can be caused by environmental factors, such as trauma can lead to nail separation, you can trim off the nail plate that has been separated. If there is a localized infection, mupirocin ointment can be used. Nail separation can also be caused by psoriasis, there can be nail depression, nail peeling and other phenomena, you can use halomethasone ointment and other hormone treatment. Another common cause of nail separation is fungal infection, which can be treated with antifungal therapy such as amorolfin, itraconazole and terbinafine. If nail separation occurs, it is recommended to go to the hospital in a timely manner, the use of the above drugs need to follow the doctor’s instructions.