Appendicitis is caused by fecal stone obstruction, which leads to bacterial growth in the appendiceal cavity, so its medication needs to be selected for the main bacteria. Because the bacteria causing its infection are mainly composed of Escherichia coli, faecal cocci, anaerobic bacteria, etc., cephalosporin antibiotics can be selected, such as cefuroxime sodium, cefoperazone sodium, cefoperazone, sulbactam sodium, etc. And for anaerobic bacteria, metronidazole, ornidazole, tinidazole, etc. can be used. If the patient is allergic to cephalosporin antibiotics, drugs such as aminoglutethimide, levofloxacin and etimesine can be used. If the infection is serious and surgery is not possible, carbapenem antibiotics such as meropenem, imipenem, ertapenem, etc. can be used. However, antibiotics are not a panacea, and if appendicitis is found, surgical removal is still recommended as the first choice for radical treatment.