Recurrence of nephrotic syndrome refers to patients with nephrotic syndrome after regular treatment, edema disappears, urine protein has turned negative, blood albumin rises to normal, 24-hour urine protein quantification is less than 300mg, and urine protein is positive again when rechecked. For relapsing nephrotic syndrome, we need to actively search for the cause of relapse before giving treatment, the more common causes are infection and hormone dependence. For the former, it is necessary to actively control the infection and pay attention to keep warm to avoid re-infection. For the latter, combined immunosuppressive therapy, such as cyclophosphamide or tacrolimus, is needed. The recurrent recurrence of nephrotic syndrome tends to transform the pathological type and lead to a poorer treatment effect, which may develop into chronic renal failure, so it is important to actively search for the cause and control it to prevent this from happening.