Leg swelling in kidney disease is usually edema, also called swelling, which means more protein drop in the blood. Patients with kidney disease are prone to water and sodium retention and increased vascular permeability, so edema is a common clinical symptom in patients with kidney disease and needs to be treated actively.1. Causes of kidney disease: When kidney disease is aggravated, when urine protein increases, or when kidney function damage is aggravated, it may lead to edema. If the patient has a large amount of proteinuria, the albumin in the blood decreases, and the ability of blood to lock water decreases, there can be leakage and accumulation of water into the peripheral tissue spaces or body cavities, leading to edema. In addition, if the glomerular filtration rate decreases when kidney function damage is aggravated, resulting in reduced urination and water accumulation in the body, which can also lead to the occurrence of edema; 2. Other causes: leg swelling in patients with kidney disease is first considered to be related to kidney disease, but it may also be caused by other diseases. If the kidney disease is stable, the original is not swollen, but now edema, you need to look for other causes. For example, heart failure, cirrhosis, hypothyroidism, venous thrombosis or valvular lesions in the lower extremities may cause edema to occur. Relevant tests need to be improved and clarified. The treatment of edema caused by kidney disease requires restricting the intake of water and sodium, applying diuretics to relieve edema under the guidance of a doctor if necessary, and depending on the patient’s kidney condition, some patients may need hormone and immunosuppressive therapy to reduce proteinuria as much as possible, and specific treatment for the primary kidney disease. If it is caused by other reasons, treat according to the cause.