First, why should tumors be treated comprehensively? Tumors are not only common diseases, but also difficult to treat. In the past half century, due to the progress of science and technology and the deepening of the research on the biological law of tumors as well as the continuous improvement and enhancement of surgical, radiotherapy, chemotherapy and other treatment means, the overall five-year survival rate after tumor treatment has increased from about 20% in the 1950s to about 50% now. Nevertheless, it is also gradually recognized that, due to the fact that the tumor is not treated with chemotherapy, the overall five-year survival rate has increased from about 20% in 1950s to about 50% now. People have also gradually realized that, due to the tumor in the early stage often lacks symptoms enough to cause alarm, many tumors in the early stage has occurred subclinical micro-metastasis, and, in the treatment of malignant tumors, the existing various therapeutic means, although they all have certain advantages, but they all have certain limitations. In the face of this situation, it is necessary to continue to improve the level of existing effective treatment means at the same time, planned and rational application of a variety of existing effective means, to complement each other’s strengths and weaknesses, which is why we should advocate the integrated treatment of tumors. The concept of integrated treatment Integrated treatment of tumors refers to the rational and planned application of effective treatments from various disciplines according to the patient’s physical condition, the pathological type of tumor, the extent of tumor invasion (staging) and the trend of development, and the patient’s affordability and willingness to prolong the patient’s survival period, increase the cure rate, and improve the patient’s quality of life. In 2000, Professor David Sackett, a famous clinical epidemiologist, defined evidence-based medicine as “the prudent, accurate and judicious application of the best available research evidence, combined with the clinician’s personal expertise and years of clinical experience, taking into account the patient’s affordability and willingness to make treatment decisions by a perfect combination of all three. “. The core idea is that the determination of any medical decision should be based on objective clinical scientific research evidence. The concept of integrated tumor therapy is also a concrete embodiment of evidence-based medicine in the treatment of tumors