Flesh swelling and pus next to the big tooth may be caused by apical abscess, periodontal abscess and other diseases, which can be treated by medication and surgery. 1. Apical abscess: The pus next to the big tooth, accompanied by local fluctuation, pressure pain, tooth loosening and other symptoms, most commonly seen in apical abscess, mainly due to dental caries. In this case, need to carry out root canal treatment, but also oral azithromycin capsules, metronidazole tablets and other drugs anti-inflammatory treatment. 2. Periodontal abscess: dental calculus, plaque, etc. can cause periodontitis, if not treated in time, will lead to periodontal abscess, the symptoms of pus next to the big teeth, you can use levofloxacin, amoxicillin capsules and other drugs for treatment, if the drug can not be relieved, you need to do surgical procedures to remove the pus. Patients with abscesses next to large teeth, it is recommended to go to the hospital in a timely manner, after the cause of the disease is clear, according to the doctor’s guidance for standardized treatment, the use of drugs need to comply with the doctor’s instructions.