Bone marrow aspiration (bone puncture) is the most basic diagnostic technique in hematology and is very necessary. For the purpose of clinical diagnosis, a small amount of bone marrow is extracted from the bone marrow cavity with a puncture needle at an appropriate site for laboratory testing. In clinical practice, we often encounter people who need bone aspiration and their families who do not understand or are afraid of or do not accept bone marrow aspiration. Even if they reluctantly accept it, they are still apprehensive and worried about it. In fact, there is really no need to be embarrassed by it. Bone aspiration is a common technique to take bone marrow fluid clinically. By analyzing various components and cellular morphological changes and compositional changes in bone marrow through bone aspiration, it may be possible to determine the cause of disease initially and quickly. It is suitable for the diagnosis, differential diagnosis and treatment follow-up of various hematological diseases, and also for the examination of protozoa and bacteriology. The puncture site is generally chosen from the anterior superior iliac spine of the pelvis, commonly known as the hip bone; the posterior superior iliac spine, the bony prominence on both sides of the sacral spine and above the hip, is also chosen. These two bony surfaces are flat, easy to fix and easy and safe to operate. The sternal stalk is also an ideal site for puncture, the so-called precordial site, where the bone marrow is abundant and the bone is thin. Because the patient faces the puncture operation when puncturing there, some people feel afraid and less often choose it. In contrast, for infants and children under 2 years of age, the lower leg is generally chosen to be performed below the anterior aspect of the tibial ramus. Due to the bleeding tendency of hemophiliacs, bone marrow puncture is clinically prohibited. There are also local skin infections that should be avoided. Some people mistakenly believe that the bone marrow fluid extracted by bone marrow aspiration may damage the essence of the human body and are reluctant to undergo the examination, but in fact the bone marrow fluid required for bone marrow examination is very small, usually about 0.1-0.2 ml, while the total amount of normal bone marrow fluid in the human body is about 260 ml, so the bone marrow fluid extracted during bone marrow aspiration is insignificant compared to the total amount of the human body. Regeneration. Therefore, even if the bone marrow needle enters the bone, it will not cause any damage to the body, so it is clinically necessary to do it. Some people fear that bone marrow aspiration is painful, but this is unnecessary. When the local skin and periosteum are anesthetized before the puncture, it is a little painful, but soon after the anesthetic takes effect, the pain disappears. Properly performed, there is no danger and no residual effects. Some diseases, especially some blood disorders, are difficult to diagnose without this test. If the condition requires it, it should be done without hesitation. Even if the bone marrow proves to be normal after the test, the mental burden of the disease is removed because the blood disorder is ruled out. Therefore, do not be embarrassed by the bone marrow aspiration.