The clinical manifestations of myeloproliferative disorders, according to the etiology and pathogenesis, are generally based on toxicity, stasis and deficiency. The toxin that causes myeloproliferative disorders is often Yang toxin, which is hot in nature and can invade the blood and disturb the liver, resulting in dizziness and swelling due to the incandescent liver meridian and hyperactive heart fire, headache like cracking, tinnitus and red eyes, irritability, little sleep, constipation, epistaxis of the nose and teeth, and red tongue and number of veins. In combination with the Western medical examination: the bone marrow proliferation is obviously active, especially in one system, and the blood picture shows that the cell count of this lineage is significantly higher than normal, and the cells of other lineages are also proliferated or suppressed, and infantile cells of granular and red lineages can be seen at various stages. This is a sign of toxicity in Chinese medicine that offends the marrow and disturbs the blood. There are also purple skin and mucous membranes, subcutaneous petechiae, epistaxis, epistaxis, dark tongue and astringent pulse. Stasis blocking the cerebral veins can be seen as stroke and insensitivity; stasis blocking the cardiac veins can be seen as chest paralysis and heart pain; stasis blocking the meridians can be seen as pulse paralysis and edema; stasis affecting the hands and feet can be seen as bruising and burning pain in the fingers and toes, or even gangrene. 3, deficiency Due to individual differences and the stage of the disease, deficiency of qi, blood, yin and yang have their own focus, but kidney deficiency is the root, and deficiency of kidney yin is the key to deficiency. At the beginning and middle stages of the disease, patients see evidence of kidney yin deficiency, spleen qi deficiency, heart and liver blood deficiency, and at the end of the disease, all deficiencies and yang, deficient yang out, cold extremities, dripping cold sweat, and weak pulse. In combination with modern medicine, the blood picture is also abnormal due to the inhibition of normal cell growth by malignant cell proliferation in the bone marrow. The clinical manifestations of each disease are different. In true erythrocytosis, blood stasis is important, and the heart and liver are hot and burning; in primary thrombocytosis, blood stasis is also obvious, and the disease is mostly damaged in the meridians, and stasis in the veins is more common; in chronic granulocytic leukemia, the poisonous evil is more important, and the poisonous heat is mixed with stasis; in myelofibrosis (chronic type), positive deficiency is prominent, and deficiency and stasis are mutually seen.