When the voice starts to be hoarse in the late stage of lung cancer, it is mostly caused by the paralysis of vocal cords due to the compression of recurrent laryngeal nerve by the tumor lesion. If the late stage of lung cancer manifests as obstructive pneumonia, obstructive pulmonary atelectasis accompanied by metastasis of distant or proximal lymph nodes, or if the late stage of lung cancer is accompanied by metastasis of multiple organs, such as liver, heart, intestines, brain, bone and other metastases, at this time, when the lung cancer is accompanied by hoarseness of voice, it can not be treated with surgery, but only be given with chemotherapy, targeting or immunotherapy to prolong the survival time. immunotherapy to prolong the survival time. If the patient has sensitive gene mutation, the median survival time can be up to 2-3 years with targeted drug treatment. However, if there is no sensitive gene mutation and the effect of chemotherapy is unsatisfactory, the survival time of lung cancer patients is about one year or even shorter. If the lung cancer causes hoarseness, but the lung cancer is confined to the same side of the lung, including mediastinal lymph node metastasis, you can seek surgical treatment from a thoracic surgeon to remove the lesion to relieve the symptoms of laryngeal recurrent nerve compression, and with post-operative chemotherapy or targeted therapy, the survival time can also be prolonged.