Most leukemias do not have a fixed fever pattern. Fevers in leukemia are often caused by infection, with acute leukemia patients experiencing a sudden, acute high fever and chronic leukemia patients experiencing a persistent low fever. In addition to fever, the patient may also have severe bleeding symptoms, which may be accompanied by an enlarged spleen, enlarged lymph nodes and pallor. In chronic leukemia, the fever progresses slowly and the symptoms of fever are not obvious. The typical symptoms are an increase in peripheral white blood cell count, which may be accompanied by unnoticeable weakness, loss of appetite and excessive sweating. For the treatment of leukemia fever, for chronic leukemia caused by a mild low-grade fever can be taken physical therapy to cool down, drink more water, put wet towels and other non-pharmaceutical treatment, for acute leukemia patients need to choose to give appropriate drug therapy on the basis of physical cooling. In general, it is not possible to determine whether a person has leukemia by virtue of the fever pattern alone, and relevant tests are needed to determine this. Regardless of the cause, if there is a persistent high fever or frequent low fever, it is necessary to go to the hospital for diagnosis and examination and active treatment in a timely manner.