What we must know about female infertility

  What do you know about female infertility? Do you know the basic knowledge about the treatment of these diseases that cause infertility? In this issue, we will introduce several common ways of treatment for female infertility.  (1) Infertility caused by tubal inflammation, adhesions and obstruction.  The most common clinical cause of infertility in women is infertility caused by tubal factors, accounting for about 40% of female infertility. Causes of tubal incompetence include pelvic inflammatory disease, tuberculosis or endometriosis. If a tubal ligation has been performed in the past, tubal revascularization can be performed in anticipation of natural conception. Treatment: (1) Drug therapy. Tubal inflammation causing tubal obstructive infertility is mainly chronic inflammation, so most medical institutions use medication, especially Chinese herbal medicine such as enema. (2) Conventional surgical treatment: Tubostomy, adhesion separation, tubal anastomosis, uterine tubal implantation, etc. can be performed on the diseased fallopian tubes if conservative treatment is ineffective. After the operation, natural conception is expected or artificial insemination can be performed to help conception according to the situation. (3) IVF: For patients with ectopic pregnancy or other factors after bilateral tubal resection and obstruction caused by tuberculous tubal inflammation and chronic tubal inflammation adhesions, the effective method to help pregnancy is IVF, which will be introduced later. Ge Mingxiao, Reproductive Medicine Center, Guangzhou General Hospital, Guangzhou Military Region (2) Infertility caused by polycystic ovary syndrome.  The incidence is 20% in women of reproductive age and accounts for about 75% of anovulatory infertility. Clinical manifestations include irregular menstruation, anovulation or sparse ovulation, infertility, hirsutism, obesity, bilateral ovarian polycystic enlargement, and endocrine disorders. The principles of treatment are based on: 1) for young obese patients in the early stage, lifestyle change, exercise, dieting, weight reduction, and for light patients in the early stage, the menstrual cycle can be normalized and natural conception can occur after changing poor diet and lifestyle; 2) medication: women of childbearing age with fertility requirements are treated mainly with ovulation promotion and fertility treatment, and must be medicated under the guidance of a specialist and followed up according to medical advice. 3) medication Patients with fertility requirements can also be treated surgically, but surgical treatment is not commonly used at present; 4) assisted reproductive technology for fertility treatment, for patients with refractory polycystic ovary syndrome who have not conceived after more than 6 cycles of ovulation promotion and have fertility requirements, assisted reproductive technology (artificial insemination or IVF) is used.  (3) Endometriosis.  When endometrial tissue with growth function appears in other parts of the body than the mucosa covering the uterine cavity, endometriosis is called endometriosis. The incidence of endometriosis has increased significantly in recent years and is now one of the common gynecological diseases. Endometriosis is present in 12%-48% of patients undergoing laparoscopy for infertility. The disease is generally seen only in women of childbearing age, mostly in women aged 25-45 years, and in those who do not develop it before menarche, the ectopic endometrial tissue may gradually atrophy and be absorbed after menopause or removal of the ovaries. The treatment plan for patients with endometriosis combined with infertility is individualized based on a comprehensive analysis of the patient’s condition and wishes, age, years of infertility, ovarian function, clinical stage, previous surgical history, and the patient’s level of awareness. 1) young patients with mild disease can expect natural conception and artificial insemination to help conception; 2) patients older than 35 years, infertility for more than 3 years, recurrent endometriosis, and Patients with more than 3 times of IUI without pregnancy can consider IVF for pregnancy; 3) Patients older than 40 years old, with infertility for more than 3 years, with reduced ovarian function, and with mild disease can directly undergo IVF for pregnancy.  Experts remind you that you should take good contraceptive measures when you do not plan to conceive or when the conditions are not available, prevent abortion and medical abortion after an unwanted pregnancy, take appropriate contraceptive measures after abortion, avoid intercourse during menstruation, pay attention to menstrual hygiene, and prevent uterine cavity and fallopian tube infections caused by reproductive tract infections, which may lead to endometritis, uterine cavity adhesions, fallopian tube adhesions and obstruction, resulting in infertility. If you have scanty and irregular menstruation, please seek medical attention in time. If you are pregnant, do not abort at will. Early patients with polycystic ovary syndrome can have natural pregnancy, but some patients are unaware of their polycystic ovary syndrome, and abortion can aggravate endocrine disorder and lead to difficulties in conceiving later.