Problems faced by people who give birth again at an advanced age – increased perinatal complications If a pregnant woman has a poor reproductive history in addition to her advanced age, and gives birth again after a long period of time, the following situations will be more serious. (1) Preterm labor There is a close correlation between advanced age and preterm labor. Advanced age is an independent factor in preterm labor. At the same time, older pregnant women are prone to hypertension, diabetes mellitus and other chronic diseases, which indirectly lead to the occurrence of preterm labor. (2) Small for gestational age High age is an independent influence on fetal growth restriction, the higher the age of the pregnant woman, the higher the risk of fetal growth restriction, pregnant women older than 35 years old and older than 40 years old are independent risk factors for intrauterine growth restriction. Possible confounding factors include chronic hypertension during pregnancy, diabetes mellitus and aneuploidy variants. (3) Fetal intrauterine death High age is an independent influence on fetal death. The probability of stillbirth is significantly higher in women older than 35 years of age, and older second-trimester pregnant women need to be more attentive to fetal movement in the middle and late trimesters and to have close prenatal checkups. Obstetricians also need to pay attention to this population and work together to reduce fetal mortality.