For each suspected kidney disease, the following questions should be noted: 1. Does the patient really have kidney disease? 2. If so which nephrotic syndrome does he belong to? 3. what is the underlying disease of this syndrome? 4. the degree of kidney function impairment. The following are the specific clinical manifestations of several nephrotic syndromes: 1. Acute glomerulonephritis syndrome with rapid onset, hematuria, proteinuria, tubular urine, edema and hypertension, and in severe cases, combined with oliguria and transient impairment of renal function. 2.Acute glomerulonephritis syndrome has a rapid onset and develops rapidly, with oliguria or even anuria, hematuria, proteinuria, tubular urine, edema, and often mild hypertension. It resembles severe acute nephritis at first onset, often with progressive anemia, renal impairment, and uremia within a few weeks to months. 3. Asymptomatic proteinuria and/or hematuria There are no clinical manifestations such as edema, hypertension, or renal impairment, but mainly mild to moderate proteinuria (less than 2.5g/24h) and/or hematuria. Clinically often called occult glomerulonephritis, this type of glomerular disease is currently one of the most neglected types, because of its lack of obvious pain and performance is not paid attention to, according to the relevant authoritative evidence-based medical reports, the national average prevalence rate in 9.9 ~ 13%, if not actively diagnosed and treated to clarify its cause, day by day, about 45% of patients will develop renal function damage after 10 years, at this time It is too late to “mend the fold”. Therefore, it needs to be taken seriously.