Dietary factors Lack of adequate dietary intake and poor dietary structure are important factors in constipation, and lack of dietary fiber and adequate water intake can lead to constipation. Psychological and social behavioral factors Children are prone to prolonged and deliberate stool-holding behavior for various reasons, which can lead to dilatation of the rectum and low colon, prolonged fecal retention, dry and hard stools, and fecal impaction, resulting in constipation. On the other hand, lack of good defecation habits and failure to master the correct way of defecation are common causes of constipation in infants and children. Abnormal intestinal motility Abnormal intestinal motility includes colonic transmission motility disorder and anorectal motility disorder. Colonic dysmotility is the cause of slow-transmission constipation, and the pathophysiological mechanism is not clear. Pathological alterations of the colonic nervous system and intestinal smooth muscle are the main causes of colonic kinetic abnormalities. abnormalities in the distribution and function of Cajal interstitial cells are important factors in intestinal kinetic disorders. Rectal-anal motility disorders manifest as outlet obstruction-type constipation, with common causes such as anal sphincter incoordination and pelvic floor muscle spasm syndrome. Changes in neurotransmitters and receptors related to intestinal motility are important causes of abnormal bowel motility. Abnormal levels of gastrointestinal hormones can cause abnormal gastrointestinal dynamics. About 40 gastrointestinal hormones have been identified, such as gastrin, vasoactive intestinal peptide, and 5-hydroxytryptamine. Effects of intestinal microecology The intestinal microecological environment of children with FC differs from that of the normal population, but the causal relationship between FC and changes in intestinal flora is not certain. A good intestinal microecological environment contributes to a shorter colonic transit time, which may be related to the breakdown of intestinal lumen contents by probiotics to produce lactic acid and short-chain fatty acids, which can act on intestinal nerves and stimulate intestinal peristalsis, thus promoting defecation. In conclusion In summary, FC pathogenesis is associated with many factors, especially the relationship between abnormal intestinal dynamics and altered intestinal microecological environment and FC is gaining attention. It is of great clinical significance to further explore the potential pathogenesis of FC and find effective treatment pathways.