Thick pimples on the face are inflammatory pimples that are more serious. It may be related to the following reasons: First, insufficient keratinization of the hair follicle itself, resulting in the blockage of the hair follicle opening, forming the basis for inflammation. Secondly, the androgen level is higher during puberty and the hormone level is unstable. Androgens favor the synthesis of oil secretion, which aggravates the greasiness of sebum and leads to the synthesis of large amounts of Propionibacterium acnes. Third, staying up late and not getting enough rest aggravates the degree of hormonal disorder, inducing the occurrence and aggravation of acne. Fourth, spicy and stimulating diet, alcohol, barbecue, etc., can also aggravate or induce pustular acne. Fifth, in the early stage of inflammatory acne, appropriate treatment (such as topical fusidic acid ointment, etc.) is not given, resulting in aggravation of inflammation and formation of purulent secretions.