Obesity-induced proteinuria can be cured if it is not due to renal organic damage; it may be difficult to be cured if it is due to renal organic lesions such as obesity-associated glomerulopathy, diabetes mellitus and other pathologic factors. Obesity-induced proteinuria can be cured if it is not caused by organic damage to the kidneys, such as after consuming a large amount of high-protein diet or strenuous exercise, usually after removing the causative factors and actively controlling body weight. If obese patients with obesity-related glomerulopathy or with diabetes and other diseases that can cause organic changes in the kidneys, and their kidneys have undergone irreversible pathologic changes, and recurrent proteinuria and other corresponding renal damage manifestations, it is very difficult to completely cure. It is recommended that patients with proteinuria seek medical attention in time, under the guidance of a professional physician to clarify the cause of the disease and then actively standardize the treatment, so as not to aggravate the condition.