For patients with kidney stones who have obvious symptoms such as fever, frequent urination, urinary urgency, painful urination and chills, they can be treated by oral anti-inflammatory drugs, common drugs such as macrolides, penicillins and cephalosporins are more effective. If kidney stone patients have bacterial infection, common bacteria are E. coli, you can take oral penicillin drugs, such as piperacillin sodium tazobactam sodium for injection, azithromycin, cefdinir, etc. If the symptoms are serious to seek medical attention in time, you can use antibiotics through intravenous drip, and with the use of ureteral dilating drugs, such as intravenous cefoperazone sulbactam, intramuscular injection of progesterone, etc. If the above methods are not effective, it is recommended to remove the stones by extracorporeal shock wave lithotripsy or minimally invasive surgery, which can effectively relieve the discomfort caused by kidney stones, drink more water, urinate more, and increase exercise appropriately to help the small stones to discharge by themselves.