The etiology and pathogenesis of gout are not well understood. Primary gout is congenital, caused by a combination of genetic and environmental factors, the vast majority of which are impaired uric acid excretion, with a certain family susceptibility. Secondary gout is mainly due to renal disease, drugs, tumor chemotherapy or radiotherapy. The cause of idiopathic gout is unknown.
Gout is a heterogeneous group of diseases caused by purine metabolism disorders and/or uric acid excretion disorders, which are clinically characterized by elevated serum uric acid, recurrent acute arthritis, gouty stones and joint deformities, uric acid renal calculi, glomerular, tubular, interstitial, and vascular renal lesions.
Gout is mainly categorized into 3 types: primary, secondary and idiopathic, with primary gout accounting for the majority.
The prevalence of gout varies widely due to the influence of geographic, ethnic, and dietary habits, and increases with age and with the elevation and duration of serum uric acid concentration.
The etiology and pathogenesis of gout are still unclear. It is mostly believed that primary gout is congenital, caused by a combination of genetic and environmental factors, and the vast majority of which are impaired uric acid excretion, with some family susceptibility. Secondary gout is mainly due to renal disease, drugs, tumor chemotherapy or radiotherapy. The cause of idiopathic gout is unknown.
If gout-related discomfort occurs, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor to improve the relevant tests to clarify the diagnosis, and follow the doctor’s instructions to standardize the diagnosis and treatment.