Definition, classification and treatment principles of amenorrhea

Amenorrhea is divided into primary amenorrhea and secondary amenorrhea: 1. Primary amenorrhea is defined as: age over 14 years, secondary sexual characteristics have not developed; or age over 16 years, secondary sexual characteristics have developed and menstruation is still coming.

2. Excited amenorrhea is defined as: cessation of menstruation for 6 months after the establishment of normal menstruation, or cessation of more than 3 cycles according to one’s original menstrual cycle.

According to endocrinology, amenorrhea can be divided into: hypothalamic amenorrhea, pituitary amenorrhea, ovarian amenorrhea, uterine amenorrhea, and abnormal development of the lower reproductive tract.

According to the WHO classification, there are three categories: 1. Type I: no endogenous estrogen production and no organic hypothalamic pituitary lesions; 2. Type II: endogenous estrogen production and normal FSH and LH secretion; 3. Type III: elevated FSH suggesting ovarian failure.

The treatment principles of amenorrhea: mainly divided into etiological treatment, endocrine treatment, and treatment for fertility requirements.

Etiological treatment is the key: and identifying the cause requires a comprehensive medical history, physical examination, gynecological examination, laboratory tests, other examinations, etc. Endocrine therapy needs to be tailored to the individual, with rational use of drugs for the applicable population. For those with fertility requirements, the treatment plan is determined according to their amenorrhea classification.