Botulinum toxin (AX) is a neurotoxin containing high molecular protein produced by Clostridium botulinum, which is the most toxic biotoxin known among natural toxins and synthetic agents, and it mainly inhibits the release of acetylcholine from nerve endings, causing a decrease in muscle tone. At present, there are only two brands of botulinum toxin in China, namely “BOTOX” from the United States and “Hengli” from China, and “BOTOX” from the United States, which has the first international market share. Since 2005, we have introduced the injection technology and treated thousands of patients with botulinum toxin injections for muscle spasms, achieving more satisfactory results. Answer: The purpose of botulinum toxin injection treatment is to improve the internal unfavorable factors for patients to carry out functional rehabilitation of limbs and to alleviate the problem of poor rehabilitative training caused by muscle spasm of limbs, so timely and regular rehabilitation training should be carried out after botulinum toxin injection. 2.Is there a rebound phenomenon of limb spasm after botulinum toxin injection? Answer: Botox injection is valid for 3-4 months, patients should seize the rehabilitation treatment in these 3-4 months, some patients have better active muscle training effect can counteract the muscle spasm of antagonist muscle, then there is no need to repeat the injection. 3.How much does Botox cost? Answer: American “BOTOX” costs about 1800 RMB/pc, Chinese “Hengli” costs about 800 RMB/pc, and it is recommended to use American “BOTOX” for large dose injection. 4.Is there any side effect of Botox injection? Answer: There are almost no side effects that are harmful to health and life, but after injection, patients may experience muscle weakness, which is caused by the original muscle strength due to spasm, not the real muscle strength, in addition, there will be some bleeding or skin diagnosis, clinically the drug does not need to conduct skin tests. 5.When can I inject Botox if I have muscle spasm? Answer: Our recommendation is the earlier the better, for example, the golden recovery time for stroke is 3 months, so it is recommended that botulinum toxin injection can be given as soon as the spasm appears in the limb, and from our 10 years of experience, the earlier this drug is used, the better.