The skull is one of the hardest bones in our body and plays an important role in protecting brain tissue and maintaining a stable intracranial environment, which is essential for normal life functioning. Therefore, if a cranial defect occurs, it should be repaired in a timely manner. In addition, the soft tissues inside the skull are not protected by the hard shell and may be easily damaged by external forces; secondly, the unstable intracranial pressure caused by skull defect may also affect the normal operation of the life activities inside the skull. The external manifestation is that it may lead to frequent headache and dizziness, in addition to the patient’s fear of pulsation, expansion and collapse of the defect area, as well as fear of sunlight, vibration and even noisy sound. It may also cause lack of concentration and memory loss, and some patients show depression, fatigue, reticence and low self-esteem. Therefore, it is necessary to perform cranial repair surgery in time after cranial defect. It is necessary to emphasize that the material of cranial repair is also important. Our widely used polyether ether ketone PEEK material is currently a very good material, this material can be shaped in three dimensions according to the patient’s skull data, highly restore the anatomical structure of the skull, in addition it is basically the same performance in elasticity, hardness, insulation, stability and other aspects of the autologous cranial bone, no rejection reaction, and will not interfere with CT, nuclear magnetic examination, etc., is an excellent cranial bone replacement material, become the cranial bone It is a new favorite in the world of cranial bone repair.