Patients with lupus erythematosus can have children, because lupus erythematosus rarely involves the reproductive system, so the fertility of patients is normal. However, patients with lupus erythematosus who want to have children need to have the following conditions: First, the condition of lupus erythematosus is stable, patients do not have combined kidney, lung, heart or central nervous system involvement, and they can prepare for pregnancy only after the condition activity is stable for more than six months. Secondly, patients need to stop using methotrexate, leflunomide, cyclophosphamide and other drugs that have an impact on the fetus before preparing for pregnancy, and they need to stop taking them for more than six months. Third, patients with lupus erythematosus need to follow up with the rheumatology and obstetrics clinics to assess their condition and should closely monitor whether the condition of lupus itself is active and whether the growth of the fetus is normal throughout the process of pregnancy.