Lupus erythematosus generally occurs in women between the ages of 20 and 40 during their childbearing years, a time when women are faced with the need to have children once they have lupus erythematosus, so can lupus erythematosus have children? Is lupus hereditary? How long can I live with lupus erythematosus? This is a difficult problem for female patients. Here is a detailed answer for you: Since lupus erythematosus patients are prone to miscarriage in the first three months of pregnancy, and the last three months and postpartum can cause aggravation of the disease, it is controversial whether lupus erythematosus patients can get pregnant. In our clinic, we have observed that most female patients marry, get pregnant and give birth based on the basic remission of the disease. The disease is still in remission after childbirth, but certain conditions must be met. For example: (1) Basic remission for more than 6 months. (2) Negative anti-cardiolipin antibody. Positive patients are prone to miscarriage and stillbirth. (3) Prednisone maintenance dose of less than 15 mg or no hormone. (4) The pregnancy should be followed up regularly under the observation of a specialist and delivered in an experienced hospital obstetrics department. (5) The fetus is protected by the placenta’s ability to oxidize prednisone to its inactive 11-ketone form. Therefore, prednisone administration to the mother has no effect on the fetus. To prevent deterioration of the disease during pregnancy and postpartum, the dose should be increased depending on the disease. The original dose can be resumed in stable cases. (6) Dexamethasone and betamethasone cannot be oxidized by placental enzymes and can affect the fetus, so patients taking these hormones should be switched to prednisone. (7) During pregnancy and lactation, more calcium should be supplemented, otherwise it will accelerate the osteonecrosis of the patient. (8) The dose of prednisone during lactation should be less than 15 mg per day and not more than 30 mg per day. (9) Salicylates, non-steroidal anti-inflammatory drugs, and antimalarials are contraindicated in pregnant women. Immunosuppressants should also be discontinued. Therefore, female patients should pay attention to contraception in their daily life, try to use male condoms for contraception, women should not take oral contraceptives for a long time, clinical trials have confirmed that some contraceptives can also induce or aggravate lupus. If these conditions are met, it is safe to get pregnant!