The human “skull” exists to protect the central command “brain” and, to a lesser extent, the bony scaffolding of the orbit, nasal cavity, mouth and face. Many people suffer from cranial defects caused by irresistible external forces, which make it necessary for patients to undergo cranial repair. What is the purpose of cranial defect repair? The brain tissue is easily injured twice without the shielding effect of normal skull, and at the same time, skull defect can cause various symptoms and affect the appearance, so many such patients need to undergo cranioplasty, the purpose of which is to restore the normal stable state of intracranial pressure as soon as possible, and to reduce the drastic changes in intracranial pressure due to skull defect, which can damage the brain function. It is usually considered that cranial repair should be performed more than 3-6 months after debridement and decompression, and for patients with infection, it should be extended to at least 6 months after debridement and decompression. If the time is too long, the local skin scar will be firm and not easy to heal after surgery, and the skin and meninges or brain tissue will be closely adhered, which increases the difficulty of separation during the operation and causes more damage to the skin and brain tissue. The skin flap collapse time is too long, and it is easy to cause flap shrinkage and ischemic necrosis after suture tension of the skin edge. PEEK (polyether ether ketone) is a special engineering plastic with better histocompatibility, high stress resistance, and perfect shaping, which is increasingly used in clinical practice for precise cranial repair, PEEK is a bionic bone that is highly compatible with autologous cranial bone and is comparable to autologous cranial bone in terms of elasticity, heat transfer, hardness, and stability. The performance of PEEK is comparable to that of autologous cranial bone in terms of elasticity, heat transfer, stiffness and stability, especially for pediatric patients, who can better adapt to the growth and development of autologous cranial bone.