Patients with acromegaly will have early onset aura symptoms, usually starting with encroachment on the extremities, and may experience weakness in the hands and feet, muscle throbbing, easy fatigue, and atrophy, which may spread upward. Aggravation may result in difficulty swallowing, difficulty speaking, respiratory failure, and may result in loss of emotional control, laughing or crying, and decreased judgment. Acromegaly, also known as motor neuron disease, is associated with damage to upper motor neurons and lower motor neurons. When the motor nerve cells in the central nervous system of an acromegaly patient are violated, the muscles will gradually atrophy and become weak, which can further lead to paralysis and the body feels like it is frozen. Acromegaly should be diagnosed as early as possible, and neuroprotective and supportive treatment should be given as soon as possible. Clinical treatment with Liruvotide is commonly used, and there is no drug that can completely block the further progress of the disease.