How is inert B-cell lymphoma treated?



B-cell inert lymphoma, including follicular lymphoma, marginal zone lymphoma, lymphoplasmacytic lymphoma and other subtypes, often slow progression, recurrent recurrence, common treatments include immunochemotherapy or radiation therapy of the involved field.

1. Disease characteristics: there are subtypes of follicular, marginal zone, lymphoplasmacytic, and condyloma, which progress slowly and recur repeatedly. Painless progressive lymph node enlargement is an important clinical feature, and unexplained fever, night sweats, and weight loss are common systemic symptoms.

2.Treatment

(1) Chemotherapy: bendamustine, cyclophosphamide, azithromycin, epirubicin, vincristine, prednisolone, etc. Adverse reactions such as loss of appetite, nausea, vomiting, stomatitis, etc. are often seen.

(2) Radiation therapy for the affected field can be used in the early stage, or it can be applied in combination with chemotherapy for the lesion limited or consolidation therapy after chemotherapy, or for the recurrence site.

(3) Hematopoietic stem cell transplantation is the use of allogeneic donor or the patient’s own hematopoietic stem cells via peripheral vascular infusion, which can re-establish normal hematopoietic and immune functions.

During the treatment of B-cell inert lymphoma, the patient’s response to treatment should be evaluated every 2~3 sessions to avoid delay. It is recommended to determine the treatment plan under the guidance of the doctor to avoid blindly using drugs by oneself.