High serum alanine aminotransferase 105U/L is commonly found in liver diseases, such as viral hepatitis, alcoholic liver disease, cirrhosis, etc., which need to be treated according to different causes.
1. Viral hepatitis: the most common is viral hepatitis B, which requires antiviral drugs such as entecavir. Entecavir needs to be taken for a long period of time and cannot be cut off by oneself. Sudden stopping of the drug may lead to severe acute deterioration of hepatitis.
2. Alcoholic Liver Disease: some patients can return to normal after strict abstinence from alcohol. In addition to alcohol cessation, hepatoprotective drugs such as polyene phosphatidylcholine can be taken to reduce hepatocyte degeneration and fibrosis.
3. Cirrhosis: first of all, we need to treat the cause of the disease, such as anti-HBV, HCV treatment, alcohol cessation and so on. Hepatoprotective drugs such as glycyrrhizin, glutathione and ursodeoxycholic acid can also be used.
In addition, high serum alanine aminotransferase can also be seen in some non-hepatic diseases, such as acute myocardial infarction, dermatomyositis, progressive myasthenia gravis, pulmonary infarction, etc., and serum alanine aminotransferase can be restored to normal after treatment of the primary disease.
If the serum alanine aminotransferase is elevated, it is necessary to go to the hospital in a timely manner, under the guidance of the doctor for targeted treatment.