Gallbladder adenoma is a type of neoplastic polyp of the gallbladder. Compared with non-neoplastic polyps and other neoplastic polyps of the gallbladder, it has a higher chance of malignant transformation and is currently considered a precancerous lesion. Therefore, in principle, patients with adenoma of the gallbladder should undergo surgery as soon as possible, with laparoscopic cholecystectomy being the first choice. For patients who are suspected to have cancerous gallbladder adenoma, a rapid pathological examination should be performed intraoperatively, and the operation should be decided according to the final result. If cancerous lesions occur, they will be treated according to the principles of gallbladder cancer. However, if the cancerous lesion is only confined to the mucosal layer, laparoscopic cholecystectomy can be performed, but the gallbladder should be kept intact during the removal process to avoid intra-abdominal implantation and metastasis. If the cancer has invaded the muscular layer or plasma membrane, wedge resection or even hemihepatectomy of the liver is needed, and lymph node dissection should also be done to ensure that the margins of the cystic duct or bile duct are negative.