When older men experience urinary symptoms, most of them think of prostate enlargement, a disease that is more familiar to older people. However, very little is known about prostate cancer. Prostate cancer usually develops after the age of 50, and 95% of the cases occur in older men over 60 years old. Prostate cancer has no symptoms in the early stage, and even if there is discomfort, it is not enough to attract the attention of patients. When the tumor enlarges and compresses the urethra, it is often confused with prostate enlargement. In China, about 80% of patients first find distant metastases before prostate cancer is detected. At this time, the lesion is already in advanced stage and the prognosis is poor. How can prostate cancer be detected at an early stage? 1. Rectal finger examination. This is the simplest, most economical and practical method. Commonly speaking, by touching the prostate gland with the doctor’s index finger, many asymptomatic prostate cancer patients can be detected and can have a chance of early diagnosis and treatment. If prostate nodules are found, the possibility of prostate cancer is suspected and one should further undergo a prostate puncture biopsy to confirm the diagnosis. 2.Serum prostate-specific antigen (PSA) test. The PSA in the blood is not high under normal circumstances (not higher than 4ng/ml), but increases when prostate cancer and other prostate disease states are present, and is currently the most sensitive tumor marker for screening prostate cancer. Patients should avoid tests or operations that stimulate the prostate and cause a high PSA before the examination, such as prostate massage, cystoscopy, catheterization, transrectal ultrasound, prostate puncture biopsy and transurethral resection of the prostate. If the PSA is elevated, it should be rechecked once. If it is still elevated and those who are obviously due to inflammation or other influencing factors are excluded, the possibility of prostate cancer is suspected and a prostate puncture biopsy should be performed. 3. Rectal ultrasonography. This means that the ultrasound probe is placed into the rectum like a rectal exam, without any injury and only minor discomfort. This test has an elevated effect on serum PSA, so it should be performed after a blood draw. Patients with nodules on rectal exam, elevated serum PSA, or suspicious lesions on ultrasound should undergo a transrectal prostate puncture biopsy. This is the ultimate means of confirming the diagnosis of prostate cancer. By using an organic combination of the three-step process of rectal screening, serum PSA and rectal ultrasound, most prostates are expected to benefit from early or earlier detection and have a chance for curative treatment.