Prostate cancer is usually asymptomatic in the early stage, but when the tumor invades or obstructs the urethra or bladder neck, symptoms similar to lower urinary tract obstruction or lower urinary tract irritation will occur, and in severe cases, acute urinary retention, hematuria, and urinary incontinence may occur. In late stage, when bone metastasis occurs, it will cause bone pain, pathological fracture, anemia, and spinal cord compression leading to lower limb paralysis. A consensus has been reached by experts in China that routine PSA and rectal finger examination should be performed for men over 50 years of age with lower urinary tract symptoms (including urinary frequency, urgency, painful urination, hematuria, and urinary retention), and for the population of men with a family history of prostate cancer, regular examination and follow-up should begin at age 45. PSA should be performed in men with abnormal rectal examinations, clinical signs (such as bone pain, fractures, etc.) or imaging abnormalities.