Every year, oncology colleagues will carefully read the annual cancer report published in the United States, in which the American Cancer Society estimates the number of new cancer cases and deaths in the United States in the current year, and compiles cancer incidence, mortality, and survival rates, and compares and analyzes them with historical data to produce various beautiful charts. The 2017 report has just been published in the CA Journal, so get a taste of it while it’s still hot. You may say, “What does the U.S. data have to do with me? The history books have not learned, the division of the long technology to control the barbarians, know yourself and know the other side, a hundred battles will not be dangerous. In addition, most of the data in the NCCN guidelines in clinical practice are from the United States? You know, CA is the world’s top medical journal, no one. The three great journals Cell, Nature, Science, can only be considered CA’s little brother. Just like you walk in the jungle, people do not know Chen Jinan, called heroes also in vain, CA is the jungle Chen Jinan. Not read a few articles on CA embarrassed to mix in the academic circle na. As the amount of data is relatively large, we choose a few points to study. Figure 1: Trends of cancer incidence (1975 ~ 2013) and mortality (1975 ~ 2014) in the United States As the above figure shows, both the incidence and mortality of cancer are higher in men than in women. In the table below, the incidence rate of men is 20% higher than that of women, and the mortality rate is 40% higher. Table 1 Gender differences in cancer incidence and mortality rates from 2009 to 2013 What are the differences between men and women in terms of estimated cancer incidence rates in 2017? See chart below. For males, the top three new cases are prostate cancer, lung cancer, and colorectal cancer. For women, the top three new cases are breast cancer, lung cancer, and colorectal cancer. Figure 2 Top 10 new cases of cancer in the United States What are the differences between men and women in terms of predicted cancer mortality in 2017? See the chart below. The top three cancer deaths for men were lung, colorectal, and prostate cancers. The top three cancer deaths for women are lung, breast, and colorectal cancers. Figure 3: Top 10 cancer deaths in the U.S. What accounts for the difference in cancer rates between men and women? The article indicates that it is not quite clear, but in some way it has to do with life circumstances, endogenous hormones, and the complex interactions between the two. Well, the authors give ambiguous answers. The reason for women’s longevity, which is popular in China, is because women can cry out when they are stressed to release their emotions and stress, while men like to carry on. The actual fact is that you can find a lot of people who are not able to get a good deal on this. 2. cherish life and stay away from tobacco Figure 4 Trend of cancer incidence (1975 ~ 2013) and mortality (1975 ~ 2014) in the United States Still this graph, this time we look at the two yellow lines in the graph, that is, the overall incidence and mortality of cancer are on a decreasing trend. Why? The main reasons are the steady decrease of smokers and the advancement of early detection and treatment. In the case of lung cancer, for example, mortality rates fell by 43 percent from 1990 to 2014 for men and 17 percent from 2002 to 2014 for women due to increased awareness of the health risks of smoking and widespread tobacco control measures that have led to a reduction in tobacco use. Despite this progress, in many parts of South America, 40% of all cancer deaths in 2014 were caused by smoking. If you think about the country, whether it’s a restaurant, elevator, park or bus stop, you can always see the uncle smoking, and do not care whether there are other people around, to be honest I really want to see this situation to dislike him, but afraid to fight him. It’s time to lose weight. There are differences in cancer incidence and mortality rates between states in the United States, and one of the factors leading to the differences is obesity, which is another important risk factor in addition to smoking. Liver cancer (one of the most deadly tumors) and uterine cancer mortality rate increased rapidly, are closely related to obesity. In the country before obesity called fat, now it seems that this is not a good thing, thin point not only beautiful, but also healthy. We always like to compare children to the flowers of our country, how about the flowers of the United States? The number one mortality rate for children aged 1 to 14 in the United States is accidents. This really makes me cold sweat, if you have children really need to hold steady. For example, the child after school, and then busy to pick up a little, you say you do not pick up, others for you to pick up how to do? The road is foggy and you can’t see the road, so accidents can easily happen. Back to the topic, cancer is the second mortality rate of children in the United States. Looking again at the age distribution of disease, leukemia (76% lymphoid leukemia) accounts for 29% of all childhood cancers (including benign and junctional malignant brain tumors). Brain and other neurological tumors accounted for 26% of childhood cancers, the second most common. The third most common tumors were lymphoma and reticuloendothelial cell tumors (11%), almost half of which were non-Hodgkin’s lymphoma. the most common type of tumor in adolescents aged 15-19 years was lymphoma (21%), almost 2/3 of which were Hodgkin’s lymphoma. Brain and other neurological tumors accounted for 17% of cases, followed closely by leukemia (14%), germ cell and gonadal tumors (12%), and thyroid cancer (11%). Melanoma accounts for 5% of cancers in this age group. Although the incidence of pediatric tumors has increased slightly at a rate of 0.6% per year since 1975, the incidence has stabilized in recent years. However, the 5-year survival rate improved significantly from the mid-1970s to 2006-2012, from 58% to 83% for pediatric cancer patients and from 68% to 84% for adolescent cancer patients. However, survival rates vary by tumor type, as shown in the table below. Table 2 Five-year relative survival rates for children aged 1 to 19 years in the United States