Patient: June 2008 After surgery in Shandong Qilu Hospital on June 30, 2008, he was discharged from the hospital with 25 times of radiotherapy from August 20 to September 26. On February 21, 2009, no recurrence or metastasis was found in the local regional hospital, but the doctor suggested that there should be 4-6 cycles of chemotherapy again, considering the toxic side effects of chemotherapy, so I would like to consult Director Shen whether chemotherapy is necessary. Shen Zhan, Department of Medical Oncology, Shanghai Sixth People’s Hospital: Many of the pathological types of hypopharyngeal cancer are hypofractionated and undifferentiated cancer, both of which are prone to metastasis, so the possibility of metastasis can be minimized by adding chemotherapy after standardized radiotherapy. Chemotherapy is indeed more harmful to people, but when used properly, it can achieve the greatest benefit with the least cost.