In general, it is not recommended to drink alcohol after vaccination because vaccines mainly work by regulating the immune mechanism of the body. Drinking alcohol after vaccination may affect the vaccination effect, aggravate the allergic reaction caused by the vaccine, and may even increase the side effects of the vaccine. Therefore, patients should avoid drinking alcohol after vaccination to avoid affecting the recovery process of the organism after vaccination and leading to adverse consequences.1. Affecting the effect of vaccine: The immune function of the organism will be temporarily affected after vaccination, and drinking alcohol will increase the burden on the liver and kidneys. The alcohol in wine has a negative effect on the metabolism of the body, which may affect the effect of the vaccine on the body. In addition, the alcohol in the body after drinking may react with the active ingredients of the vaccine, which may also lead to the effect of the vaccine being affected; 2. Affect the recovery of the organism: some patients may have fever, dizziness, vomiting and other symptoms after vaccination, and drinking may aggravate the adverse reactions of the vaccine, which also increases the risk of adverse consequences of the vaccine, thus affecting the recovery of the organism; 3. After vaccination, there may be various inflammatory allergic reactions such as redness, swelling, pain and fever at the vaccination site. Similar symptoms can also be caused by alcohol allergy and alcohol poisoning after excessive alcohol consumption. If both happen by chance at the same time, or at a similar time, it may affect the doctor’s diagnosis at the time of medical consultation and cause misdiagnosis. Patients should try to avoid drinking and smoking after vaccination, and should also try to avoid the intake of spicy, cold and other stimulating foods to avoid inducing various adverse reactions.