The typical symptoms of chronic bronchitis are cough and sputum, or wheezing and shortness of breath. The onset of the disease is slow and the duration of the disease is long, with onset lasting 3 months or more each year and continuous for 2 or more years. Chronic bronchitis is mainly treated symptomatically. Symptomatic treatment includes cough suppression (e.g. compound licorice combination, compound methoxyphenamine, dextromethorphan, etc.), expectoration (acetylcysteine, bromhexine, amiloride, myrtle oil, etc.) and wheezing (theophylline, beta2 agonists or anticholinergic inhalation therapy). When patients are co-infected, anti-infective treatment is required, mostly based on the common pathogens in the patient’s location, with the appropriate anti-infective drugs such as levofloxacin and amoxicillin. Particular attention should be paid to smoking cessation and inhalation of harmful gases or fumes in life.