The clinical manifestations of amebic granuloma of the appendix are usually limited abdominal pain and intermittent diarrhea, sometimes positive for occult blood in the stool, and a soft salami-like mass may be palpable in the right lower abdomen. What should we pay attention to in terms of diet in amebic granuloma of the appendix? When cecum amebic granuloma attacks, it is best to use clear liquid diet, such as rice soup, almond tea, clear soup, light tea, lotus root powder, thin noodle soup, peeled red date soup, salty food should be the mainstay, and after the disease is relieved, it can gradually transition to less residue semi-liquid diet, and minimize the use of gas-producing and fatty food, such as milk, soy milk, sucrose, etc. When the abdominal pain is severe, water should be fasted, so that the stomach and intestines fully rest, when the abdominal pain is reduced, and then discretionary diet, should prohibit cold, stimulating food, such as vinegar, chili, onion, ginger, garlic, pepper, etc., and do not use excitatory foods such as strong tea, coffee, cocoa, etc., when cooking, mainly light, with less fat or other seasonings. In addition, pay attention to the consumption of nutritious food. Eat more high-protein foods and high-vitamin foods to ensure that the organism has enough various nutrients to prevent anemia and malnutrition. For those who are anemic and malnourished, foods rich in protein and heme iron should be added to the diet, such as lean meat, chicken, fish, liver, loin and other offal. Foods high in vitamins come with dark fresh vegetables and fruits, such as green leafy vegetables, tomatoes, eggplants, red dates, etc. It is best to eat 2 to 3 fresh hawthorn at each meal to stimulate the secretion of gastric juice. This granuloma mostly does not need surgical treatment, and treatment with drugs (chloroquine, diiodohydroxyquine, methotrexate) will have good results. Untreated amebic granuloma of the cecum can lead to complications such as peritonitis, abscesses around the cecum and fecal fistulas after surgical resection, so a correct preoperative diagnosis is important. Barium enema can only prove that it is a cecum lesion and cannot be differentiated, so it is often misdiagnosed as a cancer and surgically removed, and sometimes the main manifestation of chronic intestinal obstruction can be misdiagnosed as intestinal tuberculosis or limited enterocolitis, and the pathological examination after resection often reveals that there are most trophozoites and encapsulation in the lesion tissue to make a clear diagnosis.