In life, many people have the habit of staying up late, but for some young people, especially men, a very strange eye disease often in their “night battle” after a quiet surprise, so that vision suddenly decreased a lot, although the patient’s original vision is good. The actual people’s Hospital of Zhengzhou Urology Department Qu Xiaowei So, what is this strange eye disease is all about? How harmful is it to people? The so-called strange disease is actually a disease of the retina of the eye, which usually has no aura and often arrives unannounced, especially when people are more tired. It is understood that this eye disease is not rare, mainly in young and middle-aged men aged 20 to 45 years old, medically called idiopathic central plasmacytoid chorioretinopathy. At present, the incidence of this disease is still very high, of which the incidence of men is 3 to 7 times that of women, and most of them develop in one eye, but also in people who usually have normal vision. In addition, the patient’s eyes often see things distorted, such as seeing positive things as crooked, large things as small, and small things as large. One characteristic of this eye disease is that it tends to recur. After a period of time, it may heal on its own, but when people think there is nothing wrong, it will attack again, and if it is not treated in time and repeated many times, it may cause permanent damage to vision. It is most likely to occur when people are overly tired or stressed, and smoking and drinking and colds are also triggering factors. When people stay up all night, especially fatigue or stress, the amount of hormone secretion in the human body will increase, which acts on the hormone receptors in the blood vessels, easily causing vasoconstriction or spasm, so that the blood flow through the blood vessels is reduced. When there is insufficient blood supply to the small blood vessels in the eye, it will cause damage to the barrier function of the retinal pigment epithelium itself, which cannot prevent some proteins, antibodies and other macromolecules from penetrating into the retina, resulting in damage to the original structure and environment of the retina, so that the visual cells cannot function normally, thus leading to a sudden loss of vision.